WHO’s updated Bacterial Priority Pathogens List (BPPL) 2024
Context:
Recently, the WHO released its updated Bacterial Priority Pathogens List (BPPL) 2024 which highlights 15 families of antibiotic-resistant bacteria grouped into critical, high and medium categories for prioritization.
- The list provides guidance on the development of new and necessary treatments to stop the spread of antimicrobial resistance (AMR)
Relevance:
GS-2 (Health)
What is AMR?
- Antimicrobial resistance occurs when bacteria, viruses, fungi, and parasites no longer respond to medicines, making people sicker and increasing the risk of disease spread, illness and deaths.
- Increasing AMR is attributed to the misuse and overuse of antimicrobials.
- The updated BPPL incorporates new evidence and expert insights to guide research and development (R&D) for new antibiotics and promote international coordination to foster innovation.
- The updated Bacterial Priority Pathogens List (BPPL) has categorized the antibiotic-resistant bacteria into critical, high and medium.
WHO BPPL 2024:
Critical priority:
- Acinetobacter baumannii, carbapenem-resistant;
- Enterobacterales, third-generation cephalosporin-resistant; and
- Enterobacterales, carbapenem-resistant;
- Mycobacterium tuberculosis, rifampicin-resistant (included after an independent analysis with parallel tailored criteria, and subsequent application of an adapted multi-criteria decision analysis matrix).
High priority:
- Salmonella Typhi.
- Shigella spp.
- Enterococcus faecium
- Pseudomonas aeruginosa
- Non-typhoidal Salmonella
- Neisseria gonorrhoeae
- Staphylococcus aureus, methicillin-resistant
Medium priority:
- Group A streptococci, macrolide-resistant
- Streptococcus pneumoniae, macrolide-resistant
- Haemophilus influenzae, ampicillin-resistant
- Group B streptococci, penicillin-resistant
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